Researchers at Princeton University have recently developed a technique named RNA prime flow that have allowed scientists to look at RNA molecules within individual cells. Thus, they have used this technique in order to look at replicating viral particles in cells of mice. This in turn has allowed the scientists to arrive at a very complete and precise method to track yellow fever virus replication in immune system cells!
This discovery is very exciting, as while there is already a Yellow Fever Virus Vaccine, Yellow Fever is a flavivirus that is very similar to other flaviviruses, Dengue and Zika virus that do NOT have a vaccine currently developed. Thus, a complete and thorough understanding of yellow fever virus replication could contribute towards the development of new vaccines that could help to save lives across the globe.
-- Ashley Jowell