There are two companies Arsanis and Adimab which focus on
developing monoclonal antibodies, and their most recent target has been RSV.
They have just gained a worldwide license to antibodies targeting RSV which
were discovered at Adimab. They discovered the antibodies using optimized
yeats-based platforms. In the current plan Adimab’s panel of antibodies will be
released to Arsanis which will evaluate them and select the best therapeutic.
This is an important step as currently there are no therapeutics for RSV which
is a very common virus in fection and is highly contagious. It is particularly
dangerous to elderly and immunocompromised people. This is not the only company
that has its eyes set on RSV. NovaVax has a RSV vaccine candidate in phase 3
trials and Ablynx is in phase 2a trials of a RSV inhalable nanobody for
infants. We shall see which treatment method becomes standard practice in the
near future.
Vander Harris
1 comment:
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