The city of New York has a microbiome of its own, and Dr.
Jane M. Carlton wants to sequence it. With a team of graduate students, Dr.
Carlton, a geneticist, is sampling the sewage from each NYC neighborhood to map
the city’s microbial diversity – the viruses, bacteria, and other pathogens
hiding in residential and commercial sewage, animal waste, and groundwater
run-off. By isolating these pathogens and sequencing their genomes, Dr.
Carlton’s team hopes to better prevent and prepare for outbreaks, as well as to
understand current infectious disease trends and the evolution of circulating
pathogens. Of particular interest is tracking antibiotic-resistant bacteria –
for example, MRSA and Clostridium difficile – in the sewage system. Dr. Eric
Alm is developing a tool to make this sequencing dream a reality. In the works
is a smart sewage device that can analyze the content of public refuse and
sewage, and then relay this data back to relevant research teams and public
officials. If they can bring this program to fruition, it could have vast
implications in terms of the health and well being of our urban centers. It’s a
lofty goal, but luckily there are many graduate students eager to dig deep into
our sewage.
- Emma Rastatter
4 comments:
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