Ebola continues
to be a tender subject. 8,500 Africans have already died in this outbreak, and
the virus doesn’t seem to be slowing down. Additionally, there seems to be a
shortage of antibodies used for ZMapp and other experimental anti-Ebola drugs.
Currently, these drugs rely on the blood of survivors, which has limited
production. It would be a real mis-steak not to try and ramp up production.
One solution has been to genetically engineer cows that
produce human antibodies.
These cows actually have pieces
of human DNA that allow them to produce human anti-Ebola antibodies. Each cow can
produce 30-60 liters of blood plasma every month—about 500-1000 human doses.
The company testing this approach, Canadian pharmaceutical manufacturer
Tekmira, has been working on experimental drugs for Ebola and Hantavirus. While
this approach is promising, the cow-derived drugs haven’t been shown to work
for Ebola Makona (which has mutations in many of the sites targeted by ZMapp),
although it looks better against Ebola Zaire (which ZMapp seems to be helping
against).
During his recent State of the Union Address, President Obama cited the outbreak and the progress on a
vaccine as reasons for the US Government to keep funding scientific research.
Will the drugs produced from these cows send Ebola over the hill once and for
all? Or will we have to mooove on to another solution? 
http://sputniknews.com/science/20150119/1017086971.html
http://www.nbcnews.com/storyline/ebola-virus-outbreak/mutant-ebola-virus-may-evade-drugs-study-finds-n289896
http://www.jefferson.edu/university/news/2014/08/vaccinating-cows-could-answer-the-ebola-serum-shortage.html
http://www.nydailynews.com/life-style/health/ebola-cure-genetically-engineered-cattle-article-1.2083778
--Joe Getsy
--Joe Getsy
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