After receiving a $17.9 million from the National Institute of Allergy and Infectious Diseases, Versatope Therapeutics is set to develop a “universal” influenza vaccine that can cover more viral strains and last longer than current vaccines. The prophylactic treatment takes a novel approach at combating influenza by targeting the Matrix-2 protein that is conserved across different strains of influenza. The protein is displayed on the outer surface of bacteria and delivered in vesicles where it can be recognized by immune cells to subsequently bolster a defense against pathogens with the antigen. The concept has been proven in vivo, allowing Versatope to commence Phase I clinical trials around 2021 to test vaccine safety and dose limits. If this technology comes to fruition, we could make large strides in preventing influenza for the long-term, especially in populations that may not have the resources to get a new vaccine each year. Additionally, the new vaccine appears to stimulate an immune response up to two-times quicker than standard immunizations, thereby building up immunity at shorter time scales. Hear from the developers here: https://www.news-medical.net/news/20191024/Universal-influenza-vaccine-developed-at-Cornell-is-set-for-human-clinical-trials.aspx
~Avi Kaye
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