Sunday, October 1, 2017

ZIka Outbreak- The effects of a single mutation


It has been two years since the Zika crisis has occurred, when it finally reached South America after originated from Uganda. The outbreak caused abnormal birth defects on infants such as microcephaly (abnormally small heads) and scared many citizens worldwide. However, Zika has been known for more than half a century (1947)  to be a relatively harmless virus, so many scientists have been mystified by why it had come to pose such a dangerous threat these past two years.

The answer was found by a group of Chinese scientists who discovered that a small mutation in Zika’s genetic makeup made the virus more dangerous. This small mutation change was due to a single amino acid change from asparagine to serine, which created a more lethal strain of Zika. This discovery could possibly lead in aiding the development of a vaccine for the Zika virus. This is extremely important because experts say that the virus could return in the future and cause another big outbreak. Currently, five to six vaccines are already in human trials but because Zika has become less active this past year, it has been difficult to find an effective vaccine. According to Anthony Fauci, the head of the National Institute of Allergy and Infectious Disease, one of the biggest priorities is to develop a vaccine because viruses like Zika don’t usually disappear, but cause another outbreak in a few years.



-       Jessica Ngo

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