A recent study out of the University of California, San Diego School of Medicine proposes a new understanding regarding how Zika Virus is able to infect a fetus' brain cells. The researchers are calling the strategy a "Trojan Horse". Their findings suggest that Zika Virus is able to infect core cells in the brain of a fetus that later become essential to the immune response.
Indeed, Dr. Alysson Muotri explains that "Zika virus can infect these early microglia, sneaking into the brain where they transmit the virus to other brain cells, resulting in the devastating neurological damage we see in some newborns." The microglia that Zika virus is able to infect directly transports the virus into the Central Nervous System which then allows it to attack the brain and cause the microcephaly that has been reported among patients infected with Zika virus.
The study has only been performed at very preliminary stages. However, the results suggest great promise for the future. The researchers believe that maybe these microglia cells may be a good place to target therapeutics. By targeting the potentially largest transmitting agent of Zika Virus within the body, the therapy would hopefully prevent transmission all together into the fetuses Central Nervous System.
Source: http://www.idse.net/Emerging-Diseases/Article/10-17/Zika-Virus-Uses-Trojan-Horse-Strategy-to-Infect-Fetal-Brain-Cells/45109
-Alexandra
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