Since 2014, more than 500 children have had a condition
called acute flaccid myelitis, a loss of muscle control of arms and legs, without
good explanation. The leading explanation was that a normal viral infection
turned into AFM, but little evidence pointed this way. Now, patient spinal
fluid potentially links the group of viruses known as enteroviruses to AFM. One
particular strain, EV-D68, had several outbreaks coinciding with cases of AFM,
and several children with AFM also presented with some of the typical symptoms
of EV-D68 presentation, a mild respiratory infection. Days before the triggering
of AFM, reports of coughs and muscle aches were common. Though in the past,
tests for enteroviruses in the spinal fluid have come back negative, in a recent
study, about 69% of the cases had elevated antibodies against enteroviruses
versus 7% of controls. Though this research does not help understand the predisposition
for AFM or what might connect enteroviruses to AFM, it is evidence of potential
association.
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