Wednesday, February 27, 2008

A promising combination vaccine for Ebola and Marburg using VLPs!

Whoa! This is amazing! So exciting! So many exclamation points are warranted!!!

Scientists at USAMRIID have announced the creation of a promising combination vaccine for Ebola and Marburg which has been shown to be 100% efficacious in cynomolgous macaques. This breakthrough vaccine for filoviruses is composed of virus-like particles (VLPs) and is totally non-infectious in nature-- just like the Gardisal HPV vaccine! Monkeys treated with the VLP based vaccine were then challenged with lethal doses of virus and none developed signs of infection while all of the control animals succumbed to the agents of hemorrhagic fever.

VLPs are likely now to be the leading candidate for human filovirus vaccine development due to their high safety, efficacy, and immunogenicity. This is a truly exciting development and the primary researcher, Dr. Kelly Warfield, hopes that the vaccine will be in human trials in a matter of years.

Check out the news release here.

Check out a more scientifically rigorous description of the work here.

yours in filo-mania (!),


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