Saturday, November 11, 2017

Norovirus, asymptomatic? (11/9/17)

The majority of cases of human gastroenteritis are caused by a single bug: norovirus (Norwalk virus). Known as the "winter vomiting bug" or the "winter vomiting disease", this virus is of the Calici family and has been around for sometime, having some twenty-nine different genotypes recorded across three different groups. The earliest cases of labelled gastroenteritis likely caused by this virus were in the late 1920's (documented by a fellow named Zahorsky); in the late 1962, however, a notably large outbreak of gastroenteritis causing nausea, diarrhea, and vomiting (lasting anywhere from half of a day to a full day) popped its head up in Norwalk, Ohio, giving the virus its common name. It wasn't until four years later, however, that the virus was isolated and imaged using EM technology, giving the scientific community a name, a particle, and a rudimentary structure to explain this common infection with a vast array of transmission techniques (aerosolization via vomit, fecal-oral, fomites, water-borne, food-borne (including filter feeders)).
Furthermore, past cases of asymptomatic infection are well-described. Indeed, it has been shown that even asymptomatic individuals are capable of shedding virus into their surrounding environments. But, a new article posted by a Japanese virology team has discovered that more people are likely asymptomatic norovirus carriers than previously anticipated or, at the least, the asymptomatic carriers are more important to information than previously thought. This team collected stool samples from 512 asymptomatic individuals in Indonesia, finding that 14 of them had norovirus infections (and were likely able to shed infectious virus). Additionally, it was found that some individuals had signs of recurrent/repeated infection by the same or different strains of the virus (though the ones detected were all of the same genotype group).
This study's conclusions, therefore, indicate that norovirus infects individuals asymptomatically at a much higher rate than believed to be the case. While this was performed in a subtropical climate, it could have implications on the the broader study and assessment of norovirus's viral profile.

Hate to noro see-ya-go, but peace out V

-javarcia ivory



http://www.health.gov.au/internet/publications/publishing.nsf/Content/cda-cdna-norovirus.htm-l~cda-cdna-norovirus.htm-l-2
https://www.sciencedaily.com/releases/2017/11/171106100154.htm
https://www.cdc.gov/norovirus/preventing-infection.html
http://www.who.int/ith/mode_of_travel/communicable_diseases/en/

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