A study stated that children who received annual flu vaccines developed robust neutralizing antibody responses that are not strain specific, thus providing strong protection against flu. The benefit of broadly neutralizing antibodies is that they are not strain specific and can therefore provide protection against diverse strains or subtypes of influenza virus.
Researchers evaluated immune responses in serum samples from participants of a cluster-randomized control trial. The original trial compared the community-level protection mediated by either inactivated virus (IIV) or live attenuated virus (LAIV) vaccination in children. To examine serologic broadly neutralizing antibodies induction, researchers compared prevaccination microneutralization (MNT) titers to titers after three influenza seasons. They found higher titers in vaccinated participants compared to controls. Specifically, 43% of vaccinees had at least a fourfold increase of MNT, compared with 13% of controls.
Therefore, annual flu vaccine is encourage especially in children.
--wenqi
No comments:
Post a Comment