Dryvax — produced by scraping virus off the skin of infected calves — is being replaced in federal vaccine stockpiles by a more modern product manufactured in laboratories.
Dryvax was unusually dangerous for a vaccine, blamed in recent years for triggering heart attacks and a painful heart inflammation in some patients.
Dryvax was created in the late 1800s, by the company that became Wyeth Laboratories. Wyeth was a primary U.S. manufacturer of smallpox vaccine by the mid-1940s, and was the only company left making it by the early 1960s, said Dr. D.A. Henderson, a University of Pittsburgh vaccine expert who played a key role in international smallpox eradication efforts.-- Nidhi
Link: http://news.yahoo.com/s/ap/20080301/ap_on_he_me/smallpox_vaccine
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