Wednesday, March 18, 2015

Longer-term CMV treatment proves more effective in babies

For my new & hot blog this time around I chose to focus on a paper out of the University of Alabama at Birmingham (UAB) recently published in the New England Journal of Medicine, "Valganciclovir for Symptomatic Congenital Cytomegalovirus Disease." I was drawn to this topic for two reasons -- first, because I was interested to learn more about any and all antivirals prescribed against herpesviruses, and valganciclovir is one. (A quick note -- valganciclovir, which is prescribed for CMV and AIDS should not be confused with valacyclovir, a variant of acyclovir usually used to combat alphaherpesviruses, and which I also blogged about!). Second, we have been discussing the teratogenic effects of CMV a lot in reviews lately, which made me interested in the applications of CMV treatment in babies in particular.

To speak to the latter point, I was startled to learn that CMV is actually the most common vertically transmitted infection, and that 1 in every 150 babies is born with the disease. This realization makes the development of treatment options and standards to ameliorate CMV all the more urgent.

The researchers in the UAB study, lead by Professor David Kimberlin, found that infants treated with valganciclovir for 6 months rather than the standard course of 6 weeks actually showed a threefold improvement in language development and hearing. Though the mechanism of this effect is still unknown, this finding is important given that one of the most common results of childhood CMV is deafness.

--Shubha Raghvendra

Sources:
-http://www.nejm.org/doi/pdf/10.1056/NEJMoa1404599
-http://www.sciencedaily.com/releases/2015/03/150304212552.htm

19 comments:

Richee said...

I was told i had Genital Herpes six months ago. of course it was the worst experience ever and i thought my life was over. So i went online to find things i can do from prevent getting outbreaks and maybe even cure this. I found someones story and how it possibly cured him. ive only had once outbreak which was the first one and i havent had another in six months. This is what i did! Vitamin D one tablet 3x a day, Vitamin C one tablet 3x a day, L-Lysine one tablet 3x a day.You can also take tea tree one tablet 3x a day, everynight after a shower i clean my lower back and make sure its nice & clean i add DSMO cream Mix with 8 drops of oregano and put it on your lower back. The DSMO cream is the one ive heard that can possibly cure it so that is the most important, im soon going to get tested again and im praying to God it comes out negative. I am very happy, that is why i am here to testify on how Dr Agumagu helped me and how he has help people that i have directed to him, i am not shy to broadcast about how i suffered of HERPES disease because i am free now, i was positive for 3 years but now i am HERPES Negative now with the help of Dr Agumagu Herbal Medicine. My dear friends, i am glad to say Dr Agumagu cured me and made my family happy again. he can cure any disease or sickness so i advice you to contact him if you have any problem you can contact him today via Email: (agumaguspelltemple@outlook.com or agumaguspelltemple@gmail.com) or call +2348158847627 whatsapp or call his number +2348158847627. He's waiting to help you....

Richee said...




I was told i had Genital Herpes six months ago. of course it was the worst experience ever and i thought my life was over. So i went online to find things i can do from prevent getting outbreaks and maybe even cure this. I found someones story and how it possibly cured him. ive only had once outbreak which was the first one and i havent had another in six months. This is what i did! Vitamin D one tablet 3x a day, Vitamin C one tablet 3x a day, L-Lysine one tablet 3x a day.You can also take tea tree one tablet 3x a day, everynight after a shower i clean my lower back and make sure its nice & clean i add DSMO cream Mix with 8 drops of oregano and put it on your lower back. The DSMO cream is the one ive heard that can possibly cure it so that is the most important, im soon going to get tested again and im praying to God it comes out negative. I am very happy, that is why i am here to testify on how Dr Agumagu helped me and how he has help people that i have directed to him, i am not shy to broadcast about how i suffered of HERPES disease because i am free now, i was positive for 3 years but now i am HERPES Negative now with the help of Dr Agumagu Herbal Medicine. My dear friends, i am glad to say Dr Agumagu cured me and made my family happy again. he can cure any disease or sickness so i advice you to contact him if you have any problem you can contact him today via Email: (agumaguspelltemple@outlook.com or agumaguspelltemple@gmail.com) or call +2348158847627 whatsapp or call his number +2348158847627. He's waiting to help you....

REAL CURE FOR GENITAL HERPES WITH PROVE said...

REAL CURE FOR GENITAL HERPES, HIV/AIDS, CANCER, DIABATES, HEPATITIS B, VAGINAL AND ITCHING BURING, WITH PROVE..

THE ONLY TRUE HERBALIST MAN WITH TEST RESULTS(PROVE) OF PEOPLE HE HAVE CURED OF MANY INFECTIONS AND DISEASES, AFTER CONTACTING 3 HERBALIST ONLINE, BUT ONLY HIM COULD CURE ME OF 2 YEARS GENITAL HERPES...HE IS REAL AND GENUINE. HIS PHONE NUMBER IS: +2348078467513 AND THIS IS HIS EMAIL: herbal.home247@yahoo.com

I am Grace Clarck by names from USA, I was diagnosed of herpes in 2015 and I tried all possible means to get cure but all to no avail until i saw a post in a health forum about herbal doctor called DR. OKUNS who prepare Herbal Medicine to cure all kind of diseases including herpes virus, at first i doubted if it was real, but i decided to give it a try, when i contact this herbal doctor via his email i bought the herpes herbal medicine from him and received it through DHL within 3 days and used it as prescribed, i tested negative within 2 weeks of usage. you can contact him via E-mail: herbal.home247@yahoo.com for any types of diseases solutions or WhatsApp/call him on: +2348078467513

MARRY HANSON said...

Thank you Dr. Okuns, your herbal medicine is a good remedy for GENITAL HERPES CUER, and Removing Warts you can contact him via E-mail: herbal.home247@yahoo.com for any types of diseases solutions or WhatsApp him on: +2348078467513

My name is Mary Hanson, am from United State. I want the general public to know how this great man called Dr. Okuns cure me from GENITAL HERPES with the herbal medicine gotten from him, he cures other diseases too like STD, SYPHILIS, BRAIN TUMOR, CANCER. My sister own was worst she suffered for Human papilloma virus HPV) for 2years and he cure me too, herbal is a great medication. he have a medicine that is 100% percent sure to cure any type of disease and you don't need to spend so much money anymore. I want you to contact Dr. Okuns on: herbal.home247@yahoo.com for any types of sickness or disease, My family is now a brand new one, so stop your worries and go get your herbal medicine now to get your family free from deadly disease. Once again thanks to Dr. Okuns you can contact him now via phone number: +2348078467513 or email him on: herbal.home247@yahoo.com

selles said...

It’s a miracle that I am alive today. I encounter herpes virus for good four (4) years, six (6) months and twelve (12) day with my calculations, before I meet the great Dr. ODUWA. I am LEOKADIA STELLA Fresno California, united state of America and I was affected with herpes virus. Herpes is a viral infection cause by the Herpes simplex virus, marked by painful, watery blister in the skin or mucous membrane or on the genitals. This was what I suffered for good four years. I have visited CVS Pharmacy in Fresno for treatment but no improvement. I meet Dr. ODUWA online while I was searching for herpes cure I read a testimony about his work. I give a try that now becomes a testimony in my life. I contacted Dr. ODUWA via his E-mail (DR.ODUWASPELLHOME@GMAIL .COM) and he did not responds to me in time and I went back to the same testimony for his mobile number and I called him immediately (+2348070685053) and he respond to my call. He welcome me as a daughter and I explain my four years situation to him and he said is done just as I have contacted him and I believed in him. Dr. ODUWA sends me some herbal medication for herpes cure and he gave me instruction on what to do and I obeyed his instruction. Changes started after three days of applying the herbal medication. I went to the same CVS Pharmacy in Fresno for test and i was herpes negative. I do not know how to thanks Dr. ODUWA for saving my life. To God be the Glory, I am living healthy with my family today.

Indeed, Dr. ODUWA is a great man

and the only thing he requested from me is to share my Testimony for the world to see for a safe living from herpes viral disease and just as I did.

God bless Dr. ODUWA for his good work....

mary care said...

I am here to testify about a great herbal spell caster called Dr.ezomo who
helped me cure my HERPES SIMPLEX VIRUS . I was infected with HERPES SIMPLEX
VIRUS in 2015, i went to many hospitals for cure but there was no solution,
so I was thinking how can I get a solution out so that my body can be okay.
So One day I went on line on the Internet to know more clue about the
Herpes Simplex Virus i came across a review of a lady saying that she got
her Herpes Simplex Virus cured by A great herbal spell caster Called Dr.
ezomo. And she also went as far to drop an email address and including Dr.
Ezomo telephone number and advise anyone to contact Dr. ezomo for any kind
of help. So i gave a try by contacting him . his email and explain my
problem to him. He told me all the things I need to do and also give me
instructions to take, which I followed properly. Before I knew what is
happening after two weeks the HERPES SIMPLEX VIRUS that was in my body got
vanished . so if you are also heart broken by any deadly diseases like
HERPES, HIV, shingles, low sperm count, HPV, Cancer, Hepatitis B, etc this
great man is extremely the best in which I have seen and applauds and if
you also need a help in curing any kind of disease, you can also email him
via: dr.ezomorootandherbals@gmail.com or whapps number +2349069171173
He can also cure so many sickness

Unknown said...

Me and my husband got diagnosed with human papilloma virus HPV for the past 3yrs. Few weeks ago I got reviewed online people who were diagnosed with human papilloma virus HPV reported online extremely positive results of Dr Oselumen helping them with natural herbal treatment and they all got cure permanently and healthy. And i also contact Dr Oselumen to help me and my husband in curing our human papillomavirus virus HPV. Ever since me and my husband took Dr Oselumen natural herbal treatment will both are totally cured and stronger and healthy. I’m so happy that me and my husbnad are now finally got cured permanently . anyone who need human papilloma virus HPV cure should email him for any incurable virus .. droselumen@gmail.com or whatsapp +2348054265852...

willian vivian said...

Good Day everyone, just want to share my experience here so you all should be more careful when contacting any herbalist for solution cos majority of the testimonies are fake and were the ones that fooled me.they all uses the same local code number (+234) cos i have been screwed by some of them.My Husband was suffering from Hsv for years and i went everywhere to get useful information that will help cure or suppress the disease.then i came across testimonies of those that took my hard earn money without any useful information or cure but they keep telling stories.about two months ago, a new staff was employed in my place of work and when He heard about my Husband Disease He was so remorseful and told me about Dr Emmanuel.but i felt it was still one of those Internet guys so i didn't call or text Dr Emmanuel. later that week, He asked me if i`ve heard from Dr Emmanuel and he gave me proof and reasons to try.well, lots of thanks to Dr Emmanuel cos as im writing this message, my Husband is CURED through the herbs that Dr Emmanuel sent to us.so after my experience, i decided to save some people from falling to the hands of SCAMS.thx for your time and if you require the service of Dr Emmanuel, you have to reach him via email: nativehealthclinic@gmail.com  or WhatsApp/Call +2348140073965
you can also reach me on  +1(862) 260-4433  
he have cure to all kinds of virus and disease,thank you 

monika love said...

I has suffered for Human papillomavirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found dr onokun is the most trustful herbalist that have herbs to cure wicked symptom's,I emailed dr onokun, for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact dr onokun with the email attach to my post. Dronokunherbalcure@gmail.com

Tamara Barrow said...

Greetings to the general public, I want to tell about how I was cured of
HIV disease by a Doctor called Dr. voodoo . I was browsing the Internet
searching for remedy on HIV and I saw a comment of people talking about how
Doctor voodoo cured them. I was scared because I never believed in the
Internet but i was convince to give him a try because i having no hope of
been cured of HIV so I decided to contact him with his email that was
listed on the comment voodoospelltemple66@gmail.com when I contacted him he
gave me hope and send a Herbal medicine to me that I took and it seriously worked
for me, am a free person now without problem, my HIV result came out negative. I pray
for you Dr. voodoo God will give you everlasting life, you shall not die
before your time for being sincere and great men. Am so happy, you can also
contact him if you have any problem Email: voodoospelltemple66@gmail.com or Add him up on
WhatsAp +234814012071

sheneanna said...

God bless Dr. maggi for his marvelous work in my life, I was diagnosed of HERPES since 2018 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched out some possible cure for HERPES i saw a comment about Dr. maggi, how he cured HERPES,DIABETES,HIV,and CANCER with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine I took the medicine as prescribed by him and 14 days later i was cured from HERPES, Dr. maggi truly you are great, do you need his help also? Why don’t you contact him through his EMAIL: drmaggiherbalhome@gmail.com call or whatsApp him on +1-917-979-6387.

Unknown said...

Hello everyone I was diagnosed of HERPES Virus in year 2000 and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HERPES virus, at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared a HERPES herbal cure and sent it to me via UPS delivery service, when i received this herbal cure, he gave me step and Instructions on how to apply it, when i applied it as instructed, i was totally cured of this disease within 17-21 days of usage, I am now free from this horrible illness disease called herpes, All thanks to Dr Iyoha for saving my life please if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: driyohasolutiontemple@yahoo.com or call : +1 407 337 9869. He also have the herb to cure: – ALS/HPV – LUPUS – HIV&AIDS, – OVARIAN CYST, – CANCER – HSV-2/KIDNEY-FAILURE -CYMBALTA – ARTHRITIS.

Unknown said...

Hello everyone I was diagnosed of HERPES Virus in year 2000 and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HERPES virus, at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared a HERPES herbal cure and sent it to me via UPS delivery service, when i received this herbal cure, he gave me step and Instructions on how to apply it, when i applied it as instructed, i was totally cured of this disease within 17-21 days of usage, I am now free from this horrible illness disease called herpes, All thanks to Dr Iyoha for saving my life please if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: driyohasolutiontemple@yahoo.com or call : +1 407 337 9869. He also have the herb to cure: – ALS/HPV – LUPUS – HIV&AIDS, – OVARIAN CYST, – CANCER – HSV-2/KIDNEY-FAILURE -CYMBALTA – ARTHRITIS.

Unknown said...

Hello everyone I was diagnosed of HERPES Virus in year 2000 and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HERPES virus, at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared a HERPES herbal cure and sent it to me via UPS delivery service, when i received this herbal cure, he gave me step and Instructions on how to apply it, when i applied it as instructed, i was totally cured of this disease within 17-21 days of usage, I am now free from this horrible illness disease called herpes, All thanks to Dr Iyoha for saving my life please if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: driyohasolutiontemple@yahoo.com or call : +1 407 337 9869. He also have the herb to cure: – ALS/HPV – LUPUS – HIV&AIDS, – OVARIAN CYST, – CANCER – HSV-2/KIDNEY-FAILURE -CYMBALTA – ARTHRITIS.

neme amber said...

Hello, everyone! I,m here to explore blogs and forum about the wonderful and most safe cure for (Herpes Virus).I was positive to the deadly virus called herpes and i lost hope because i was out casted and rejected even by my closet friends.i searched on-line to know and enquirer about cure for Herpes and i read someone testimony on how he was cured from Herpes so i decided to contact the same herbalist because i know that nature has the power to heal everything.i contacted him to know how he can help me and he told me never to worry that he will heal me with the natural herbs from God!after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via DHL and it got to me after 3 days!i used the med as he instructed me (MORNING and EVENING) and i was cured!its really like a dream but i am so happy!thats the reason i decided to also add more comment of Him so that more can be saved just like me!and if you need his help, you can email him on nativehealthclinic@gmail.com, or whatsapp +2348140073965 I,m neme amber and you can get in touch with me via nemeamber@gmail.com..Contact him for help at Herpes virus HIV/AIDS CANCER COPD BRAIN TUMOR All kind of virus and disease //...

Rebecca Eller said...

Spell to fix your broken marriage or relationship problem or after a divorce or Breakup,I was recently scam by two of them, until one faithful day i meet a man called Dr Oselumen who help me to get back to the father of my kid after we have been separated for two years,I only pay for the items required for the spell and he cast the spell for me within 24hours my ex husband called me and beg me to forgive him for everything until the end of the world he will never leave me again we are back together.if you need a real and quick love spell or you are passing through pregnancy problem Dr Oselumen is the answer, Pleas e if any body needs. LOVE SPELL,LOTTERY,PREGNANCY SPELL, DIVORCE SPELL,STOP COURT CASE AND WIN ANY COURT PROBLEM,DEATH SPELL,BUSINESS SPELL AND MANY MORE YOU MAY NEED. Email him now for your own help. via email droselumen@gmail.com add him on whatsapp line or call +2348054265852. 

juwan james said...

Hello everyone. Dr ishaiku herbs is a good remedy for herpes Virus , I was a carrier of herpes virus and I saw a testimony on how Dr. ishiaku cure Herpes Virus, I decided to contact him, I contacted him and he guided me. I asked him for solutions and he started the remedies for my health. After he finish he sent me the herbs which i took for 2 weeks before asking me to go for a check up and getting there i could not believe that i was confirm HSV 2 Negative after the test, Today i am so happy because i'm free from herpes disease with the help of Dr. ishiaku . Thank God now everything is fine, I'm cured by Dr. ishiaku herbal medicine, I'm very thankful to God for making it possible. you can reach him on his email, i strongly recommend him to any one out here looking for a cure.Contact Dr ishiaku via email: ishiakuherbalcure@gmail.com call or whatsApp him on+2348180828544

Tamara Barrow said...

Natural herbs have cured so many illness that drugs and injection cant
cure. I've seen the great importance of natural herbs and the wonderful
work they have done in people's lives. i read people's testimonies online
on how they were cured of herpes, HIV, diabetics etc by Dr. voodoo herbal
medicine, so i decided to contact the doctor because i know nature has the
power to heal anything. I was diagnosed with HIV for the past 7 years but
Dr. voodoo cured me with his herbs and i referred my aunt and her husband
to him immediately because they were both suffering from herpes but to God
be the glory, they were cured too .I know is hard to believe but am a
living testimony. There is no harm trying herbs. He is also a spell caster,
he cast spell to restore broken marriages and he cast good luck spells to
prosper and excel in life. Contact Dr voodoo on Whatsapp or call him
+2348140120719 OR email him voodoospelltemple66@gmail.com

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